C&E is ideal for small tumors with distinct borders, for primary lesions and for lesions on surfaces with minimal excess tissue . It is not recommended for large tumors, tumors invading dermis or fat, lesions with poorly defined borders, poorly differentiated squamous cell carcinomas, recurrent lesions or lesions at certain anatomic sites that have lower cure rates.
C&E is a low-risk procedure that can be performed on an outpatient basis. In contrast to surgical excision , an open wound is left that can then bleed, become infected and form a scar. The site may take one to three months to heal and appear acceptable.
Cryosurgery This technique uses liquid nitrogen at very low temperatures to freeze the skin. The
nitrogen is applied with an aerosolized spray to achieve tissue temperatures below -50¬°C (-58¬°F). The tissue is then allowed to thaw for about two minutes. This cycle is repeated two to three times.
Like C&E, cryosurgery is a low-risk procedure. It can, therefore, be used for people who cannot tolerate surgery and is also useful for anyone who is having treatment to prevent blood clotting (anticoagulation therapy).
Cryotherapy is effective for removing lesions where there is minimal excess tissue and can be used for large primary tumors. It is not useful with poorly defined lesions, poorly differentiated SCC, morpheaform BCC, recurrent lesions, lesions in areas of decreased cure rates or on the extremities (arms and legs), where there is decreased blood flow.
